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This course focuses on the injection of Botulinum toxin type A in the entire face with a safe and effective technique. The injection points based on the literature and on global faculty consensus will be demonstrated with consideration of the facial anatomy.

This course covers the anatomical changes in the face that occur with age. After completion of the course you will be able to: Describe the intrinsic and extrinsic factors of aging; recognize the signs of aging in the face, including changes in the facial skeleton, muscles, fascia, ligaments, adipose tissue and skin; possible improvements by rejuvenation techniques.

Get to know not only the musculature and fat compartments of the upper, mid and lower face, but also the key differences based on ethnicity.

Understand the regular course of the nerves and vessels and become aware of the most important anatomical variations. Avoid complications by familiarising yourself with all the risk of anastomosis of the facial arteries, which are visualized specifically in a new technique.

Cellulite is nearly universal in adult women, however, it is often misunderstood.  This course explores cellulite by examining its structure, causes and pathophysiology.  In addition, cellulite is differentiated from other anatomical structures such as laxity and anatomical junction points. Finally, the prevalence of cellulite along with current treatment options are examined.

Book this course and you will benefit from a practical guide for physicians performing aesthetic medicine. The course comprises everything you need to know to optimise outcomes such as pre-treatment considerations, facial mapping, scales, photo documentation as well as ethical considerations such as informed consents, mental health aspects and legal issues.

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This module introduces botulinum toxins, providing an overview of their history and use in aesthetic medicine. Botulinum toxin type A (BoNT/A) is reviewed in detail to explore the pharmacology, efficacy and safety profile, and how it can be employed in clinical practice to correct signs of ageing. Patient assessment and optimal management of possible adverse events will also be covered. This module consists of 3 courses.

Get to know BELOTERO®, the unique HA filler range with CPM technology for seamless dermal integration. This course will give an overview of the BELOTERO® fillers, their physical properties and practical use in aesthetic medicine. The course will enable you to select the most appropriate formulation to perform common aesthetic techniques and introduces specific injection techniques (video).

Discover RADIESSE®, the natural lifting filler for lifting and contouring with long-term collagen stimulation. This course covers physical properties, mode of action and injection techniques (video) of RADIESSE®. By following this course you will get a clear understanding how to use RADIESSE® at its best.

Discover XEOMIN® COSMETIC, the advanced botulinum toxin product, free from complexing proteins. XEOMIN® COSMETIC is proven to deliver effective and safe treatments based on a uniquely pure formulation that results in high patient satisfaction and added convenience for Health Care Professionals. This course covers practical use, techniques, correct reconstitution, dosing and storage of XEOMIN® COSMETIC. Including detailed demonstration of injection techniques for the most important areas.

XEOMEEN® is the only Botulinum toxin type A preparation approved for the combined treatment of upper facial lines (UFL), which means the treatment of glabellar frown lines, crow’s feet lines and horizontal forehead lines - both combined and as single indications in Europe. This approval is based on the first double-blind placebo controlled, Phase III study that demonstrates significant efficacy of XEOMEEN® for the treatment of single and combined UFL. XEOMEEN® treatment effects maintained for up to 120 days and are safe and well tolerated. A separate study assessing patient-reported outcomes showed that XEOMEEN® patients were significantly more satisfied with their appearance after treatment, most feeling younger and more attractive. This course has to be seen as an addition to the XEOMEEN® main course.

Get to know BELOTERO®, the unique HA filler range with CPM technology for seamless dermal integration. This course will give an overview of the BELOTERO® fillers, their physical properties and practical use in aesthetic medicine. The course will enable you to select the most appropriate formulation to perform common aesthetic techniques and introduces specific injection techniques (video).

The natural lifting filler with long-term collagen stimulation is now available with integral lidocaine. RADIESSE® Lidocaine injectable implant is a recent addition to the portfolio of Merz Aesthetics. It combines the established and proven dermal filler RADIESSE®, which stimulates the natural production of collagen, with the local anaesthetic lidocaine, to offer enhanced comfort to patients.This course has to be seen as Lidocaine special as an addition to the main course.    

Discover RADIESSE®, the natural lifting filler for lifting and contouring with long-term collagen stimulation. This course covers physical properties, mode of action and injection techniques (video) of RADIESSE®. By following this course you will get a clear understanding how to use RADIESSE® at its best.

Discover XEOMEEN®, the advanced botulinum toxin product, free from complexing proteins. XEOMEEN® is proven to deliver effective and safe treatments based on a uniquely pure formulation that results in high patient satisfaction and added convenience for Health Care Professionals. This course covers practical use, techniques, correct reconstitution, dosing and storage of XEOMEEN®. Including detailed demonstration of injection techniques for the most important areas.

Explore Cellfina ®, the treatment for the long term improvement in the appearance of cellulite.  This course provides an overview of the Cellfina® System, and its innovative technology.  A brief review of cellulite puts the Cellfina® mechanism of action into context explaining how it treats the structural cause of cellulite.  Finally, data from the Cellfina® clinical study is examined including the safety and efficacy profile.


Discover BOCOUTURE®/XEOMIN®, the advanced botulinum toxin product, free from complexing proteins. BOCOUTURE®/XEOMIN® is proven to deliver effective and safe treatments based on a uniquely pure formulation that results in high patient satisfaction and added convenience for Health Care Professionals. This course covers practical use, techniques, correct reconstitution, dosing and storage of BOCOUTURE®/XEOMIN®. Including detailed demonstration of injection techniques for the most important areas.

Discover BOCOUTURE®/XEOMIN®, the advanced botulinum toxin product, free from complexing proteins. BOCOUTURE®/XEOMIN® is proven to deliver effective and safe treatments based on a uniquely pure formulation that results in high patient satisfaction and added convenience for Health Care Professionals. This course covers practical use, techniques, correct reconstitution, dosing and storage of BOCOUTURE®/XEOMIN®. Including detailed demonstration of injection techniques for the most important areas.

BOCOUTURE® is the only Botulinum toxin type A preparation approved for the combined treatment of upper facial lines (UFL), which means the treatment of glabellar frown lines, crow’s feet lines and horizontal forehead lines - both combined and as single indications in Europe. This approval is based on the first double-blind placebo controlled, Phase III study that demonstrates significant efficacy of BOCOUTURE® for the treatment of single and combined UFL. BOCOUTURE® treatment effects maintained for up to 120 days and are safe and well tolerated. A separate study assessing patient-reported outcomes showed that BOCOUTURE patients were significantly more satisfied with their appearance after treatment, most feeling younger and more attractive. This course has to be seen as an addition to the BOCOUTURE® main course.

Discover RADIESSE®, the natural lifting filler for lifting and contouring with long-term collagen stimulation. This course covers physical properties, mode of action and injection techniques (video) of RADIESSE®. By following this course you will get a clear understanding how to use RADIESSE® at its best.

Discover RADIESSE®, the natural lifting filler for lifting and contouring with long-term collagen stimulation. This course covers physical properties, mode of action and injection techniques (video) of RADIESSE®. By following this course you will get a clear understanding how to use RADIESSE® at its best.

The natural lifting filler with long-term collagen stimulation is now available with integral lidocaine.RADIESSE® Lidocaine injectable implant is a recent addition to the portfolio of Merz Aesthetics. It combines the established and proven dermal filler RADIESSE®, which stimulates the natural production of collagen, with the local anaesthetic lidocaine, to offer enhanced comfort to patients.This course has to be seen as Lidocaine special as an addition to the main course.    


Get to know BELOTERO®, the unique HA filler range with CPM technology for seamless dermal integration. This course will give an overview of the BELOTERO® fillers, their physical properties and practical use in aesthetic medicine. The course will enable you to select the most appropriate formulation to perform common aesthetic techniques and introduces specific injection techniques (video).

Get to know BELOTERO®, the unique HA filler range with CPM technology for seamless dermal integration. This course will give an overview of the BELOTERO® fillers, their physical properties and practical use in aesthetic medicine. The course will enable you to select the most appropriate formulation to perform common aesthetic techniques and introduces specific injection techniques (video).

Get to know ULTHERAPY®, the only non-invasive procedure which is FDA-cleared to lift skin on the neck, the eyebrow, under the chin and to improve lines and wrinkles on the décolletage.

Workshop of Dr. Swift, Benelux – Anatomy

BOCOUTURE® 4 units/0.1 ml powder for solution for injection Active substance: Botulinum toxin type A (150 kD), purified from Clostridium Botulinum cultures (Hall strain), free from complexing proteins. Prescription-only medicine! Qualitative and quantitative composition: One vial contains: 50 units of Botulinum toxin type A (150 kD), free from complexing proteins, human albumin, sucrose. Due to the differences in the potency assays, unit doses are specific to BOCOUTURE®. Therefore the recommended dose units for BOCOUTURE® are not interchangeable with those for other Botulinum toxin preparations. Therapeutic indications: For temporary improvement in the appearance of upper facial lines in adults below 65 years when the severity of these lines has an important psychological impact for the patient:
  • moderate to severe vertical lines between the eyebrows seen at maximum frown (glabellar frown lines) and/or
  • moderate to severe lateral periorbital lines seen at maximum smile (crow's feet lines) and/or
  • moderate to severe horizontal forehead lines seen at maximum contraction.

Contraindications: Hypersensitivity to the active substance or to any of the excipients, generalised disorders of muscle activity (e.g. myasthenia gravis, Lambert-Eaton syndrome), infection or inflammation at the proposed injection site. Do not use during pregnancy unless clearly necessary. Do not use during breast-feeding. Undesirable effects: Undesirable effects usually occur within the first week following injection and are temporary in nature. They may be related to the active substance, the injection procedure, or both. Application-related: Localised pain, inflammation, paraesthesia, hypoaesthesia, tenderness, swelling, oedema, erythema, itching, localised infection, haematoma, bleeding and/or bruising. Caused by the injection procedure: Pain and/or anxiety may lead to vasovagal responses such as transient symptomatic hypotension, nausea, tinnitus, and syncope. Undesirable effects of the substance class Botulinum toxin type A: Localised muscle weakness, blepharoptosis (possibly caused by the injection technique) are an expression of the pharmacological effect. Toxin spread: When treating other indications with Botulinum toxins, undesirable effects related to spread of the toxin distant from the site of administration have been reported very rarely (exaggerated muscle weakness, dysphagia, and aspiration pneumonia with a fatal outcome in some cases). These cannot be completely ruled out with the use of BOCOUTURE®. Hypersensitivity reactions: Rare reports of severe and/or immediate hypersensitivity reactions such as anaphylaxis, serum sickness, urticaria, soft tissue oedema, and dyspnoea, sometimes either following the administration of conventional Botulinum toxin type A complex preparations alone or in combination with other active substances known to cause similar reactions. The following undesirable effects were reported from clinical experience with BOCOUTURE®: Vertical lines between the eyebrows seen at maximum frown (glabellar frown lines) Common (≥1/100 to <1/10): headache, muscle disorders (elevation of eyebrow); Uncommon (≥1/1,000 to <1/100): Bronchitis, nasopharyngitis, influenza-like illness, depression, insomnia, facial paresis (brow ptosis), eyelid oedema, eyelid ptosis, blurred vision, pruritus, skin nodule, muscle twitching, muscle spasm, sensation of heaviness, injection site: haematoma, pain, tenderness, fatigue. Lateral periorbital lines seen at maximum smile (crow's feet lines) Common (≥1/100 to <1/10): Eyelid oedema, dry eye, injection site: haematoma. Upper facial lines: Very common (≥1/10):headache; Common (≥1/100 to <1/10):hypoaesthesia , eyelid ptosis, dry eye, facial asymmetry, sensation of heaviness, nausea, injection site: haematoma, pain. Post-marketing experience: Flu-like symptoms and hypersensitivity reactions such as swelling, oedema (also apart from the injection site), erythema, pruritus, rash (local and generalized), and breathlessness have been reported. Merz Pharmaceuticals GmbH, 60048 Frankfurt/Main, Germany.
Date of revision of the text: March 2016 Further information is provided in the Summary of Product Characteristics and the Package Leaflet.
PLEASE CHECK YOUR LOCAL APPROVAL STATUS

Considering the shape of the chin you need to make a decision on the treatment.

Do you want to bring the chin more forward (anterior projection), increase the length or feminize the chin. Watch Dr. Goldie making her decision and treating a real patient.


I am the description

In this lecture by Dr. Rolf Bartsch you will experience how you could achieve good results on cellulite dimple treatment in your practice with a very easy learning curve.


 

 

A holistic treatment experience is crucial for making patients return to your practice. Especially the way you handle and consult the patient can be a decisive factor for achieving loyalty and for distinguishing yourself from other healthcare professionals.  Watch this short lesson of Arthur Swift, an expert in patient communication.


Body dysmorphic disorder (BDD) is a mental disorder by which the patient is obsessed with a perceived or minor defect in appearance. That's why there is a high probability that several of the patients visiting your aesthetic practice might suffer from BDD. But BDD often goes unrecognized. In this lecture Dr. Kemperman explains the risks associated to the treatment of patients suffering from BDD and shows ways to identify and handle BDD patients.

One of the most vital success factors when it comes to studies and publications are Good Clinical Practices.
Here you will find guidelines to help you deliver high-quality studies and publications:

  • Good Publication Practice version 3 (GPP3)
  • Recommendations of the International Committee of Medical Journal Editors (ICMJE)
  • Good Clinical Practice (GCP)
“Better studies means better publications”

Understanding the clinical outcomes of a filler treatment requires looking at several parameters such as the filler’s rheological profile. Rheology is the science dealing with the deformation and flow of matter. It takes into consideration aspects such as elasticity, viscosity and cohesivity. Watch this video to learn more about the rheology of fillers.



PUBLICATIONS 2018


BELOTERO

Cohesive polydensified matrix hyaluronic acid for the treatment of etched-in fine facial lines: a 6-month, open-label clinical trial.
Black JM, Gross TM, Murcia CL, Jones DH. Dermatol Surg. 2018 Jan 8.; DOI: 10.1097/DSS.0000000000001462

RADIESSE

Calcium hydroxylapatite treatment of human skin: evidence of collagen turnover through picrosirius red staining and circularly polarized microscopy.
Zerbinati N, Calligaro A. Clin Cosmet Investig Dermatol. 2018; 11:29–35

 

PUBLICATIONS 2017


BELOTERO

Effectiveness evaluation of two volumizing hyaluronic acid dermal fillers in a controlled, randomized, double-blind, split-face clinical study.
Kerscher M, Agsten K, Kravtsov M, et al. Clin Cosmet Investig Dermatol. 2017;10:239–47; DOI: https://doi.org/10.2147/CCID.S135441

Free radical scavenging properties of mannitol and its role as a constituent of hyaluronic acid fillers: a literature review.
André P, Villain F.; Int J Cosmet Sci. 2016;1‒6.; DOI: 10.1111/ics.12386

Late-onset inflammatory response to hyaluronic acid dermal fillers.
Bhojani-Lynch T.; Plast Reconstr Surg Glob Open. 2017;5:e1532; DOI: 10.1097/GOX.0000000000001532

Mid-face volumization with hyaluronic acid: injection technique and safety aspects from a controlled, randomized, double-blind clinical study.
Prager W, Agsten K, Kravtsov M, et al. J Drugs Dermatol. 2017;16(4):351‒357

Patient-reported outcomes following split-face injection of 2 volumizing fillers in the upper cheeks.
Prager W, Agsten K, Kerscher M.; Plast Reconstr Surg Glob Open 2017;5:e1412; DOI: 10.1097/GOX.0000000000001412

Two crosslinking technologies for superficial reticular dermis injection: a comparative ultrasound and histologic study.
Micheels P, Besse S, Sarazin D.; J Clin Aesthet Dermatol. 2017;10(1):29‒36. PMCID: PMC5300731

Ultrasound and histologic examination after subcutaneous injection of two volumizing hyaluronic acid fillers: a preliminary study.
Micheels P, Besse S, Sarazin D, et al.; Plast Reconstr Surg Glob Open 2017;5:e1222; DOI: 10.1097/GOX.0000000000001222

BOTULINUM TOXIN TYPE A

A pilot, double-blind, placebo-controlled study to assess the efficacy and safety of incobotulinumtoxinA injections in the treatment of rosacea. Dayan SH, Ashourian N, Cho K. J Drugs Dermatol. 2017;16(6):549‒54; DOI: http://dx.doi.org/10.1016/j.jaad.2017.04.102

Efficacy and tolerability of incobotulinumtoxinA for treating glabellar frown lines in Korean adults: a postmarketing observational study.
Park JY, Sung NK, Pitt JM.; Dermatol Surg. 2017 Sep 28.; DOI: 10.1097/DSS.0000000000001330

Efficacy of incobotulinumtoxinA for the treatment of glabellar frown lines in male subjects: post-hoc analyses from randomized, double-blind pivotal studies.
Jones DH, Kerscher M, Geister T, et al.; Dermatol Surg. 2017 Nov;43 Suppl 2:S235-S241.; DOI: 10.1097/DSS.0000000000001295

IncobotulinumtoxinA for aesthetic indications: a systematic review of prospective comparative trials.
Prager W, Nogueira Teixeira D, Leventhal PS.; Dermatol Surg. 2017 Apr 3. DOI: 10.1097/DSS.0000000000001076

IncobotulinumtoxinA is an effective and well-tolerated treatment for upper facial lines: results from an open-label extension period of a phase III study.
Trevidic P, Connolly SA, Biwer B, et al. Dermatol Surg. 2017;43 Suppl 3: S285‒S292; DOI: 10.1097/DSS.0000000000001416

Safety of incobotulinumtoxinA in the treatment of facial lines: results from a pooled analysis of randomized, prospective, controlled clinical studies.
Coleman WP 3rd, Sattler G, Weissenberger P, et al. Dermatol Surg. 2017;43 Suppl 3:S293–S303; DOI: 10.1097/DSS.0000000000001409l

Tailored botulinum toxin type A injections in aesthetic medicine: consensus panel recommendations for treating the forehead based on individual facial anatomy and muscle tone.
Anido J, Arenas D, Arruabarrena C, et al.; Clin Cosmet Investig Dermatol. 2017;10:413–421.; DOI: 10.2147/CCID.S138274

Treatment of lateral periorbital lines with different dilutions of incobotulinumtoxinA.
Muti GF, Basso M. J; Clin Aesthet Dermatol. 2017; 10(9):27–29

CELLFINA

A multicenter pivotal study to evaluate tissue stabilized-guided subcision using the Cellfina device for the treatment of cellulite with 3-year follow-up.
Kaminer MS, Coleman WP 3rd, Weiss RA, et al. Dermatol Surg. 2017 Jun 28.; DOI: 10.1097/DSS.0000000000001218

DESCRIBE

Evaluation of a transparent perfluorodecalin-infused patch as an adjunct to laser-assisted tattoo removal: a pivotal trial.
Biesman BS, Costner C.; Lasers Surg Med. 2017 Mar 20.; DOI: 10.1002/lsm.22659

PORTFOLIO

Communication concepts for prevention and early intervention in aesthetic medicine: consensus and literature review.
Gout U, Anand CV, Braz A, et al.;J Drugs Dermatol. 2017;16(9):859‒864

Efficacy and tolerability of incobotulinumtoxinA for treating glabellar frown lines in Korean adults: a postmarketing observational study.
Park JY, Sung NK, Pitt JM.; Dermatol Surg. 2017 Sep 28. DOI: 10.1097/DSS.0000000000001330

First consensus on primary prevention and early intervention in aesthetic medicine.
Landau M, Anand CV, Besins T, et al.;J Drugs Dermatol. 2017;16(9):846‒854

Microfocused ultrasound with visualization and calcium hydroxylapatite for improving skin laxity and cellulite appearance.
Casabona G, Pereira G. Plast Reconstr Surg Glob Open 2017;5:e1388;DOI: 10.1097/GOX.0000000000001388

Pan-Asian consensus— Key recommendations for adapting the World congress of dermatology consensus on combination treatment with injectable fillers, toxins, and ultrasound devices in Asian patients.
Chao YYY, Chhabra C, Corduff N, et al.;J Clin Aesthet Dermatol. 2017;10(7):16‒27

RADIESSE

Calcium hydroxylapatite: A review on safety and complications.
Kadouch J.A.; J Cosm Dermatol. 2017; 00:1-10. DOI: 10.1111/jocd.12326

Calcium hydroxylapatite combined with microneedling and ascorbic acid is effective for treating stretch marks.
Casabona G, Marchese P.; Plast Reconstr Surg Glob Open 2017;5:e1474; DOI: 10.1097/GOX.0000000000001474

Diluted calcium hydroxylapatite for skin tightening of the upper arms and abdomen.
Lapatina NG, Pavlenko T.; J Drugs Dermatol. 2017;16(9):900‒906

Microfocused ultrasound in combination with diluted calcium hydroxylapatite for improving skin laxity and the appearance of lines in the neck and décolletage.
Yutskovskaya Y.A., Kogan EA.; J Drugs Dermatol. 2017;16(1):68‒74. PMID: 28095536

Improved neocollagenesis and skin mechanical properties after injection of diluted calcium hydroxylapatite in the neck and décolletage: a pilot study.
Casabona G, Nogueira Teixeira D.; J Cosmet Dermatol. 2017 Dec 29.; DOI: 10.1111/jocd.12475

Restoring jawline contour with calcium hydroxylapatite: a prospective, observational study.
Baspeyras M, Dallara JM, Cartier H, et al. J Cosmet Dermatol. 2017;00:1–6.; DOI: 10.1111/jocd.12335

 

PUBLICATIONS 2016


BELOTERO

Effect of different crosslinking technologies on hyaluronic acid behavior: a visual and microscopic study of seven hyaluronic acid gels.
Micheels P, Sarazin D, Tran C et al.; J Drugs Dermatol. 2016;15(5):600–6

Hyaluronic acid fillers with cohesive polydensified matrix for soft-tissue augmentation and rejuvenation: a literature review.
Prasetyo AD, Prager W, Rubin MG, et al.; Clin Cosmet Investig Dermatol 2016;9:257–80; DOI: 10.2147/CCID.S106551

Influence of the macro- and/or microstructure of crosslinked hyaluronic acid hydrogels on the release of two model drugs.
Mondon K, Dadras M, Tillier J, et al.; J Glycobiol 5:119. DOI: 10.4172/2168–958X.1000119

Key importance of compression properties in the biophysical characteristics of hyaluronic acid soft-tissue fillers.
Gavard Molliard S, Albert S, Mondon K; J Mech Behav Biomed Mater. 2016;61:290–8; DOI: 10.1016/j.jmbbm.2016.04.001

Quantifying depth of injection of hyaluronic acid in the dermis: data from clinical, laboratory and ultrasound settings.
Micheels P, Besse S, Sarazin D, et al.; J Drugs Dermatol 2016;15(4):483–90

Safety and performance of CPM® hyaluronic acid fillers with lidocaine in the clinical setting – an open-label, multicenter study.
Kühne U, Esmann J, von Heimburg D, et al.; Clin Cosmet Investig Dermatol 2016;9:373–81; DOI: 10.2147/CCID.S115256


BOTULIUM TOXIN TYPE A

Aesthetic applications of botulinum toxin A in Asians: an international, multidisciplinary, pan-Asian consensus.
Sundaram H, Huang PH, Hsu NJ et al.; Plast Reconstr Surg Glob Open 2016;4:e872; DOI: 10.1097/GOX.0000000000000507

Efficacy and safety of incobotulinumtoxinA in Asian subjects: a pooled analysis of clinical trials in the treatment of glabellar frown lines.
Seo K, Tsai TF, Chao YYY, et al.; J Drugs Dermatol. 2016;15(9):1084–7


CELLFINA

Tissue stabilized–guided subcision for the treatment of cellulite: a multicenter pivotal study with two-year follow-up.
Kaminer MS, Coleman WP 3rd, Weiss RA, Grossman J.; Dermatol Surg. 2016;42(10):1213–6; DOI: 10.1097/DSS.0000000000000897


NEOCUTIS

Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature.
Aldag C, Nogueira Teixeira D, Leventhal PS; Clin Cosmet Investig Dermatol 2016;9:411–9; DOI: 10.2147/CCID.S116158 

A novel matrikine-like micro-protein complex (MPC) technology for topical skin rejuvenation.
Dreher F; J Drugs Dermatol 2016;15(4):457–64


PORTFOLIO

Combining microfocused ultrasound with botulinum toxin and temporary and permanent dermal fillers: safety and current use.
Fabi SG, Goldman MP, Mills DC, et al.; Dermatol Surg 2016;42:S168–S176; DOI: 10.1097/DSS.0000000000000751

Consensus recommendations for combined aesthetic interventions in the face using botulinum toxin, fillers, and energy-based devices.
Carruthers J, Burgess C, Day D, et al.; Dermatol Surg. 2016;42(5):586–97; DOI: 10.1097/DSS.0000000000000754

Consensus recommendations for combined aesthetic interventions using botulinum toxin, fillers, and microfocused ultrasound in the neck, décolletage, hands, and other areas of the body.
Fabi SG, Burgess C, Carruthers A, et al.; Dermatol Surg. 2016;42(10):1199–1208; DOI: 10.1097/DSS.0000000000000869

Validated assessment scales for décolleté wrinkling and pigmentation.
Landau M, Geister TL, Leibou L, et al.; Dermatol Surg 2016;42(7):842–52; DOI: 10.1097/DSS.0000000000000786


RADIESSE

Calcium hydroxylapatite with integral lidocaine provides improved pain control for the correction of nasolabial folds.
Schachter D, Bertucci V, Solish N; J Drugs Dermatol 2016;15(8):1005–10

Evaluation of lifting and antiwrinkle effects of calcium hydroxylapatite filler. In vitro quantification of contractile forces of human wrinkle and normal aged fibroblasts treated with calcium hydroxylapatite.
Courderot-Masuyer C, Robin S, Tauzin H, et al.; J Cosmet Dermatol. 2016;15(3):260–8; DOI: 10.1111/jocd.12215

Radiesse®: a novel rejuvenation treatment for the upper arms.
Amselem M; Clin Cosmet Investig Dermatol 2016;9:9–14; DOI: 10.2147/CCID.S93137

Rheological properties of calcium hydroxylapatite with integral lidocaine.
Meland M, Groppi C, Lorenc ZP; J Drugs Dermatol. 2016;15(9):1107–10


ULTHERAPY

Evaluation of micro-focused ultrasound for lifting and tightening neck laxity.
Baumann L, Zelickson B; J Drugs Dermatol. 2016;15(5):607–14


PUBLICATIONS 2015


BELOTERO

A blinded, randomized, split-face pilot study of bruising and pain with hyaluronic acid for correction of perioral lines using no lidocaine, lidocaine alone, and lidocaine and epinephrine.
Moradi A, Shirazi A, Moradi-Poehler J, et al.; Aesthetic Surg J 2015;35(4):443–55; DOI: 10.1093/asj/sjv043

A prospective, comparative survey to investigate practitioners' satisfaction with a cohesive, polydensified-matrix®, hyaluronic acid-based filler gel with and without lidocaine for the treatment of facial wrinkles.
Prager W, Micheels P; J Cosmet Dermatol 2015;14(2):124–9; DOI: 10.1111/jocd.12136

Cohesive polydensified matrix hyaluronic acid for fine lines.
Sundaram H, Fagien S; Plast Reconstr Surg 2015;136(5 Suppl):149S–63S; DOI: 10.1097/PRS.0000000000001835

Cohesivity of hyaluronic acid fillers: development and clinical implications of a novel assay, pilot validation with a 5-point grading scale, and evaluation of six US FDA-approved fillers.
Sundaram H, Rohrich RJ, Liew S, et al.; Plast Reconstr Surg 2015;136(4):678–86; DOI: 10.1097/PRS.0000000000001638

Hyaluronic acid filler in HIV-associated facial lipoatrophy: evaluation of tissue distribution and morphology with MRI.
Becker M, Balagué N, Montet X, et al.; Dermatology. 2015;230(4):367–74; DOI: 10.1159/000379747

Treatment of age-related mid-face atrophy by injection of cohesive polydensified matrix® (CPM®) hyaluronic acid volumizer.
Micheels P, Vandeputte J, Kravtsov M; J Clin Aesthet Dermatol 2015;8(3):28–34; PMCID: PMC4382143

Ultrastructural analysis of 3 hyaluronic acid soft-tissue fillers using scanning electron microscopy.
Flynn TC, Thompson DH, Hyun SH, et al.; Dermatol Surg 2015;41 Suppl 1:S143–52; DOI: 10.1097/01.DSS.0000452647.14389.a7


BOTULIUM TOXIN TYPE A

A prospective, neurophysiologic comparative study to assess the efficacy and duration of effect of incobotulinumtoxinA and abobotulinumtoxinA in the treatment of crow's feet.
Saybel A, Artemenko A, Nikitin S, et al.; J Drugs Dermatol 2015;14(11):1291–6

A prospective rater- and subject-blinded study comparing the efficacy of incobotulinumtoxinA and onabotulinumtoxinA to treat crow’s feet: a clinical cross-over evaluation.
Muti G, Harrington L; Dermatol Surg 2015;41:S39–S46; DOI: 10.1097/DSS.0000000000000262

A randomized, double-blind trial to investigate the equivalence of incobotulinumtoxinA and onabotulinumtoxinA for glabellar frown lines.
Kane MAC, Gold MH, Coleman WP 3rd et al.; Dermatol Surg 2015;41(11):1310–9; DOI: 10.1097/DSS.0000000000000531

Efficacy and safety of incobotulinumtoxin A for the correction of glabellar lines among patients with skin types IV to VI.
Jackson BA, Vogel MR; J Drugs Dermatol 2015;14(4):350–3

Efficacy and safety of incobotulinumtoxinA in the treatment of upper facial lines: results from a randomized, double-blind, placebo-controlled, phase III study.
Kerscher M, Rzany B, Prager W, et al.; Dermatol Surg 2015;41(10):1149–57; DOI: 10.1097/DSS.0000000000000450

IncobotulinumtoxinA in aesthetics: Russian multidisciplinary expert consensus recommendations.
Yutskovskaya Y, Gubanova E, Khrustaleva I, et al.; Clin, Cosm & Invest Derm 2015;8:297–306; DOI: 10.2147/CCID.S72301

IncobotulinumtoxinA use in aesthetic indications in daily practice: a European multicenter, noninterventional, retrospective study.
Pavicic T, Prager W, Klöppel M, et al.; Clin, Cosm & Invest Derm 2015: 8;135–42; DOI: 10.2147/CCID.S74519

Pharmaceutical, biological, and clinical properties of botulinum neurotoxin type A products.
Frevert J; Drugs R D 2015;15(1):1–9; DOI: 10.1007/s40268-014-0077-1

Patient-reported outcomes after incobotulinumtoxinA treatment for upper facial wrinkles.
Streker M, Luebberding S, Krueger N, et al.; Dermatol Surg 2015;41:S29–S38; DOI: 10.1097/DSS.0000000000000274

IncobotulinumtoxinA for the treatment of platysmal bands: a single-arm, prospective proof-of-concept clinical study.
Prager W, Bee EK, Havermann I, et al.; Dermatol Surg 2015;41:S88–S92; DOI: 10.1097/DSS.0000000000000177


PORTFOLIO

A randomized study to validate the Merz hand grading scale for use in live assessments.
Cohen JL, Carruthers A, Jones DH, et al.; Dermatol Surg 2015;41 Suppl 1:S384-8; DOI: 10.1097/DSS.0000000000000553

Consensus recommendations for optimal augmentation of the Asian face with hyaluronic acid and calcium hydroxylapatite.
Rho NK, Chang YY, Chao YY, et al.; Plast Reconstr Surg 2015;136(5):940–56; DOI: 10.1097/PRS.0000000000001706


RADIESSE

Evaluation of the Merz hand grading scale after calcium hydroxylapatite hand treatment.
Bertucci V, Solish N, Wong M, et al.; Dermatol Surg 2015 Dec;41 Suppl 1:S389-96; DOI: 10.1097/DSS.0000000000000546

A prospective, comparative, evaluator-blind clinical study investigating efficacy and safety of two injection techniques with Radiesse® for the correction of skin changes in aging hands.
Gubanova EI, Starovatova PA; J of Cutan & Aesthetic Surg 2015;8(3):147–52; DOI: 10.4103/0974-2077.167271

Calcium hydroxylapatite for augmentation of face and hands: a retrospective analysis in Italian subjects.
Muti GF, Astolfi G, Renzi M, et al.; J Drugs Dermatol 2015; 14(9):948–54

Body vectoring technique with Radiesse® for tightening of the abdomen, thighs and brachial zone.
Cogorno Wasylkowski V; Clin, Cosm & Invest Derm 2015;8:267–73; DOI: 10.2147/CCID.S75631

Complete biodegradable nature of calcium hydroxylapatite after injection for malar enhancement: an MRI study.
Pavicic T; Clin, Cosm & Invest Derm 2015:8 19–25; DOI: 10.2147/CCID.S72878

Calcium hydroxylapatite: Over a decade of clinical experience.
Loghem JV, Yutskovskaya YA, Werschler P; J Clin Aesthet Dermatol 2015;8(1):38–49; PMCID: PMC4295857



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